As women age, one of the first changes noted is in the appearance of the upper lip. As early as age 25, an overall lengthening of the upper lip is evident. Generally around 35 years of age, the lips will begin to flatten and thin out, the corners droop, and the lip lines begin to form. The lips are often the most neglected part of the most anti-aging regimens. Dehydrated skin is susceptible to weakness, flimsiness, patchiness and wrinkles.